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Commentary on the 2016 named series: Neuroimaging, inflammation and behavior

Harrison, Neil A. ORCID: 2016. Commentary on the 2016 named series: Neuroimaging, inflammation and behavior. Brain, Behavior, and Immunity 58 , pp. 48-51. 10.1016/j.bbi.2016.08.010

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Neuroimaging techniques are increasingly used to characterize the neural circuitry mediating actions of inflammation on mood, motivation, and cognition and its relationship to common mental illnesses, particularly major depressive disorder (MDD). In addition, imaging techniques such as single photon emission tomography (SPECT), positron emission tomography (PET) and magnetic resonance spectroscopy (MRS) can index effects of inflammation on specific neurotransmitters, monoamine transporters, metabolites and even activation of discrete cells such as microglia. The special named series ‘Neuroimaging, inflammation and behavior’ illustrates the power of neuroimaging techniques to characterize discrete actions of inflammation on the brain at neurochemical, cellular, regional and network levels. Combined with careful cognitive assessment and pre-clinical studies, diverse neuroimaging techniques are helping clarify the mechanisms through which inflammation acts on the brain to reorient behavior and predispose to mental and physical illnesses.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Publisher: Elsevier
ISSN: 1090-2139
Date of Acceptance: 12 August 2016
Last Modified: 25 Oct 2022 14:02

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