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Atypical herpes type 2 encephalitis associated with normal MRI imaging

Harrison, N.A. ORCID:, MacDonald, B.K., Scott, G. and Kapoor, R. 2003. Atypical herpes type 2 encephalitis associated with normal MRI imaging. Journal of Neurology Neurosurgery and Psychiatry 74 (7) , pp. 974-976. 10.1136/jnnp.74.7.974

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We describe a case of chronic atypical herpes simplex type 2 encephalitis in an immunocompromised 68 year old man presenting with headache and cognitive changes without focal neurological or MRI findings. To our knowledge this is the first described case of herpes simplex encephalitis associated with normal MRI brain imaging and non-focal neurological examination. This further expands the range of clinical presentations that may be associated with herpes simplex encephalitis and emphasises the value of PCR for herpes simplex virus in the investigation of encephalitis regardless of imaging findings.

Item Type: Article
Status: Published
Schools: Medicine
Last Modified: 25 Oct 2022 14:03

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