Al-Otaibi, Hadil Faris
2019.
Controlled delivery of antimicrobial and anti-inflammatory agents from un-cemented prosthesis.
PhD Thesis,
Cardiff University.
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Abstract
The prevalence of joint replacement procedures has increased by more than 119% in the last decade and as a result the demand for a prosthesis is very likely to increase. Uncemented prosthesis is the first-choice treatment option for patients under 68, due to its long-term and more stable fixation. The two major limitations that lead to the failure of joint replacement surgery are a prosthetic joint infection and aseptic loosening. To counter these limitations this study aimed to develop a novel composite system with dual functionality for prophylaxis from postsurgical inflammation and infection. The system is versatile safe to use in in-vitro.
Item Type: | Thesis (PhD) |
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Date Type: | Completion |
Status: | Unpublished |
Schools: | Pharmacy |
Subjects: | R Medicine > RS Pharmacy and materia medica |
Date of First Compliant Deposit: | 17 July 2019 |
Last Modified: | 29 Mar 2021 09:44 |
URI: | https://orca.cardiff.ac.uk/id/eprint/124245 |
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