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The soluble sperm factor that activates the egg: PLCzeta and beyond

Swann, Karl 2020. The soluble sperm factor that activates the egg: PLCzeta and beyond. Reproduction 160 (1) 10.1530/REP-20-0079

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Abstract

PLCzeta(ζ) initiates Ca2+ oscillations and egg activation at fertilization in mammals, but studies in mouse eggs fertilized by PLCζ knockout (KO) sperm imply that there is another slow acting factor causing Ca2+ release. Here, I propose a hypothesis for how this second sperm factor might cause Ca2+ oscillations in mouse eggs.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Biosciences
Publisher: BioScientifica
ISSN: 1470-1626
Date of First Compliant Deposit: 6 January 2021
Date of Acceptance: 30 April 2020
Last Modified: 18 Jan 2021 18:49
URI: https://orca.cardiff.ac.uk/id/eprint/137378

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Cited 3 times in Scopus. View in Scopus. Powered By Scopus® Data

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