BKC-2, a new BKC variant detected in MCR-9.1-producing Enterobacter hormaechei subsp. xiangfangensis

Martins, Willames M. B. S., Martins, Evelin R., de Andrade, Letícia K., Farzana, Refath, Walsh, Timothy R., Toleman, Mark A., Nogueira, Mara C. L. and Gales, Ana C. 2021. BKC-2, a new BKC variant detected in MCR-9.1-producing Enterobacter hormaechei subsp. xiangfangensis. Antimicrobial Agents and Chemotherapy 65 (3) , e01193-20. 10.1128/AAC.01193-20

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Abstract

We performed the characterization of a multidrug-resistant (MDR) Enterobacter spp. isolate highlighting the genetic aspects of the antimicrobial resistance genes. An Enterobacter spp. isolate (Ec61) was recovered in 2014 from a transtracheal aspirate sample from a patient admitted to a Brazilian tertiary hospital and submitted to further microbiological and genomic characterization. Ec61 was identified as Enterobacter hormaechei subsp. xiangfangensis ST451, showed a MDR profile and the presence of genes codifying new β-lactamase variants, BKC-2 and ACT-84, and the mobile colistin resistance gene mcr-9.1.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Publisher:	American Society for Microbiology
ISSN:	0066-4804
Date of Acceptance:	3 December 2020
Last Modified:	27 Feb 2022 10:51
URI:	https://orca.cardiff.ac.uk/id/eprint/138252

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