The anterior thalamic nuclei and cognition: a role beyond space?

Nelson, Andrew J. D. ORCID: https://orcid.org/0000-0002-5171-413X 2021. The anterior thalamic nuclei and cognition: a role beyond space? Neuroscience and Biobehavioral Reviews 126 , pp. 1-11. 10.1016/j.neubiorev.2021.02.047

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Abstract

The anterior thalamic nuclei are a vital node within hippocampal-diencephalic-cingulate circuits that support spatial learning and memory. Reflecting this interconnectivity, the overwhelming focus of research into the cognitive functions of the anterior thalamic nuclei has been spatial processing. However, there is increasing evidence that the functions of the anterior thalamic nuclei extend beyond the spatial realm. This work has highlighted how these nuclei are required for certain classes of temporal discrimination as well as their importance for processing other contextual information; revealing parallels with the non-spatial functions of the hippocampal formation. Yet further work has shown how the anterior thalamic nuclei may be important for other forms of non-spatial learning, including a critical role for these nuclei in attentional mechanisms. This evidence signals the need to reconsider the functions of the anterior thalamic within the framework of their wider connections with sites including the anterior cingulate cortex that subserve non-spatial functions.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Psychology
Publisher:	Elsevier
ISSN:	0149-7634
Funders:	Wellcome Trust
Date of First Compliant Deposit:	11 March 2021
Date of Acceptance:	11 March 2021
Last Modified:	06 Jul 2023 17:38
URI:	https://orca.cardiff.ac.uk/id/eprint/139626

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