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Assessing sensitivity to change of the genomics outcome scale (GOS)

Ting, Michael Sing Onn, Clarke, Angus ORCID: and McAllister, Marion 2021. Assessing sensitivity to change of the genomics outcome scale (GOS). Journal of Genetic Counseling 30 (6) , pp. 1767-1772. 10.1002/jgc4.1429

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The Genetic Counseling Outcome Scale (GCOS-24) is a 24-item patient reported outcome measure (PROM) that was developed to evaluate genetic counseling and testing services by measuring the construct of empowerment. The Genomics Outcome Scale (GOS) is a 6-item version of GCOS-24 that was designed to provide a PROM for use both within and outside clinical genetics services and reduce respondent burden. However, unlike GCOS-24, the sensitivity to change of the GOS have not yet been assessed in appropriate clinical settings. We carried out pre- and post-clinic surveys using the GOS to assess sensitivity to change of the GOS and produce before-and-after GOS data as part of a service evaluation. The survey was sent to patients attending the genetic counseling clinic for a first appointment at the All Wales Medical Genetic Service from 8 April 2019 to 18 September 2019. Patients attending disease management clinics, where genetic issues were not the primary concern, were excluded from this study. A total of 138 respondents were included in the final analysis. The result shows that empowerment scores, measured using the GOS, were significantly higher (p<0.05) after clinic attendance. The GOS shows good sensitivity to change, with a medium-to-large effect size (Cohen’s d=0.73). The result also shows that the service is delivering measurable benefits for its service users.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Additional Information: This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Publisher: Springer
ISSN: 1059-7700
Date of First Compliant Deposit: 15 April 2021
Date of Acceptance: 13 April 2021
Last Modified: 22 Jul 2023 16:14

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