Cauchi, Marija, Ball, Harriet, Ben-Shlomo, Yoav and Robertson, Neil ![]() ![]() |
Preview |
PDF
- Published Version
Available under License Creative Commons Attribution. Download (867kB) | Preview |
Abstract
As a result of significant recent scientific investment, the range of vaccines available for COVID-19 prevention continues to expand and uptake is increasing globally. Although initial trial safety data have been generally reassuring, a number of adverse events, including vaccine induced thrombosis and thrombocytopenia (VITT), have come to light which have the potential to undermine the success of the vaccination program. However, it can be difficult to interpret available data and put these into context and to communicate this effectively. In this review, we discuss contemporary methodologies employed to investigate possible associations between vaccination and adverse neurological outcomes and why determining causality can be challenging. We demonstrate these issues by discussing relevant historical exemplars and explore the relevance for the current pandemic and vaccination program. We also discuss challenges in understanding and communicating such risks to clinicians and the general population within the context of the ‘infodemic’ facilitated by the Internet and other media.
Item Type: | Article |
---|---|
Date Type: | Publication |
Status: | Published |
Schools: | Medicine MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG) |
Additional Information: | This article is licensed under a Creative Commons Attribution 4.0 International License |
Publisher: | Springer |
ISSN: | 0340-5354 |
Date of First Compliant Deposit: | 1 September 2021 |
Date of Acceptance: | 6 August 2021 |
Last Modified: | 06 May 2023 11:23 |
URI: | https://orca.cardiff.ac.uk/id/eprint/143787 |
Citation Data
Cited 4 times in Scopus. View in Scopus. Powered By Scopus® Data
Actions (repository staff only)
![]() |
Edit Item |