Jones, Andrew C., Nicholson, William I., Leitch, Jamie A. and Browne, Duncan L. ![]() |
Preview |
PDF
- Accepted Post-Print Version
Download (1MB) | Preview |
Official URL: http://dx.doi.org/10.1021/acs.orglett.1c02096
Abstract
The nickel-catalyzed cross-electrophile coupling of aryl halides and alkyl halides enabled by ball-milling is herein described. Under a mechanochemical manifold, the reductive C–C bond formation was achieved in the absence of bulk solvent and air/moisture sensitive setups, in reaction times of 2 h. The mechanical action provided by ball milling permits the use of a range of zinc sources to turnover the nickel catalytic cycle, enabling the synthesis of 28 cross-electrophile coupled products.
Item Type: | Article |
---|---|
Date Type: | Publication |
Status: | Published |
Schools: | Chemistry |
Publisher: | American Chemical Society |
ISSN: | 1523-7060 |
Funders: | WEFO and the Leverhulme Trust |
Date of First Compliant Deposit: | 18 October 2021 |
Date of Acceptance: | 3 August 2021 |
Last Modified: | 21 Nov 2024 01:15 |
URI: | https://orca.cardiff.ac.uk/id/eprint/144910 |
Citation Data
Cited 9 times in Scopus. View in Scopus. Powered By Scopus® Data
Actions (repository staff only)
![]() |
Edit Item |