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Gastro-oesophageal reflux is not a major cause of brief resolved unexplained events in infants

Jilani, Nadeem Z., Hussain, Amna, Al Ansari, Khalid and Powell, Colin V.E. 2019. Gastro-oesophageal reflux is not a major cause of brief resolved unexplained events in infants. Breathe 15 (2) , e32-e39. 10.1183/20734735.0174-2019

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The clinical scenario of an infant presenting to the emergency department with the parents reporting a history of the child stopping breathing, choking or “turning blue” at home is a well-recognised event and accounts for between 2.5 and 4.1 hospital admissions per 1000 live births [1, 2]. The infant is often back to their normal self with a normal clinical examination. This event used to be called an apparent life-threatening event (ALTE) [1] and recently it has been suggested that it should now be called a brief resolved unexplained event (BRUE) [2]. Gastro-oesophageal reflux (GOR) has long been considered to be a common reason for an ALTE and some studies have listed it as an underlying cause in up to 54% of patients [3–6]. Does the evidence support this belief?

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Publisher: European Respiratory Society
ISSN: 1810-6838
Date of First Compliant Deposit: 12 November 2021
Date of Acceptance: 3 June 2019
Last Modified: 23 May 2023 14:22

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