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Nanoparticles: their potential use in antibacterial photodynamic therapy

Perni, S., Prokopovich, Polina, Pratten, J., Parkin, I. P. and Wilson, M. 2011. Nanoparticles: their potential use in antibacterial photodynamic therapy. Photochemical and Photobiological Sciences 10 (5) , pp. 712-720. 10.1039/C0PP00360C

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Photodynamic therapy (PDT) has been proposed as a new technique to inactivate microorganisms as it does not lead to the selection of mutant resistant strains; a clear benefit compared to antibiotic treatment. PDT has also attracted the interest of nanotechnology as the effectiveness of the treatment can be greatly enhanced by the use of nanoparticles. In the last decade, different approaches to the combination of nanoparticles and PDT have been investigated in relation to the antimicrobial applications of the technique. One use of the nanoparticles is to improve the delivery of photosensitiser to the bacteria; others use the nanoparticles to improve the inactivation kinetics. A different approach utilises nanoparticles as a photosensitiser. In this review these diverse types of interactions will be described.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Engineering
Subjects: R Medicine > RM Therapeutics. Pharmacology
Publisher: Royal Society of Chemistry
ISSN: 1474-905X
Last Modified: 03 Sep 2019 08:25

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