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Life expectancy in multiple sclerosis by EDSS score

Walz, Lucas, Brooks, Jordan C., Shavelle, Robert M., Robertson, Neil ORCID: and Harding, Katharine E. 2022. Life expectancy in multiple sclerosis by EDSS score. Multiple Sclerosis and Related Disorders 68 , 104219. 10.1016/j.msard.2022.104219

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The median survival time of newly-diagnosed MS patients without severe disabilities is approximately 30-35 years. The prognosis after the onset of severe disability has not been reported. Based on Harding et al.’s 2018 study of the Southeast Wales MS registry, we calculated life expectancies according to the Expanded Disability Status Scale (EDSS). Upon loss of independent ambulation (EDSS 6-6.5; mean age 51.2) life expectancy was 13.3 additional years. At EDSS 9-9.5 (mean age 70.8) life expectancy was 1.1 additional years. These figures provide an empirical basis for discussions of advanced MS care planning.

Item Type: Article
Date Type: Publication
Status: Published
Schools: MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG)
Additional Information: License information from Publisher: LICENSE 1: Title: This article is under embargo with an end date yet to be finalised.
Publisher: Elsevier
ISSN: 2211-0348
Date of Acceptance: 4 October 2022
Last Modified: 10 Nov 2022 14:02

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