Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Nature-inspired enzymatic cascades to build valuable compounds

Sigrist, Renata, Costa, Bruna Zucoloto da, Marsaioli, Anita Jocelyne and Gonzaga De Oliveira, Luciana 2015. Nature-inspired enzymatic cascades to build valuable compounds. Biotechnology Advances 33 (5) , pp. 394-411. 10.1016/j.biotechadv.2015.03.010

Full text not available from this repository.


Biocatalysis currently is focusing on enzymatic and multi-enzymatic cascade processes instead of single steps imbedded into chemical pathways. Alongside this scientific revolution, this review provides an overview on multi-enzymatic cascades that are responsible for the biosynthesis of some terpenes, alkaloids and polyethers, which are important classes of natural products. Herein, we illustrate the development of studies inspired by multi- and chemo-enzymatic approaches to build the core moieties of polyethers, polypeptide alkaloids, piperidines and pyrrolidines promoted by the joint action of oxidoreductases, hydrolases, cyclases, transaminases and imine reductases.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Chemistry
Publisher: Elsevier
ISSN: 0734-9750
Last Modified: 14 Nov 2022 16:05

Actions (repository staff only)

Edit Item Edit Item