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Comparative evaluation of calcium hypochlorite and sodium hypochlorite on soft-tissue dissolution

Dutta, Arindam ORCID: and Saunders, William P. 2012. Comparative evaluation of calcium hypochlorite and sodium hypochlorite on soft-tissue dissolution. Journal of Endodontics 38 (10) , pp. 1395-1398. 10.1016/j.joen.2012.06.020

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Introduction: The aim of this study was to compare in vitro the tissue-dissolution properties of 5% and 10% calcium hypochlorite (Ca(OCl)2) with two concentrations (1.36% and 4.65%) of proprietary sodium hypochlorite (NaOCl) on bovine muscle tissue. Methods: The available chlorine concentration of each solution was determined using iodometric titration. Tissue specimens from bovine muscle were weight adjusted (50 ± 5 mg). Ten tissue specimens in each group were immersed in 5 mL each test solution, removed after 5 minutes, blotted dry, and weighed. The process was repeated every 5 minutes with a fresh 5-mL aliquot of the test solution for 60 minutes or until complete tissue dissolution, whichever was quickest. The percentage weight loss of the specimens was calculated over the experimental period. Results: Available chlorine concentrations of the irrigants ranged from 1.36% to 4.65%. All solutions dissolved tissue completely after 60 minutes except 5% Ca(OCl)2 (99.4% dissolution). Between the 35- and 60-minute test readings, there were no significant differences between the solutions. Chlorax (4.65% NaOCl) (Cerkamed Group, Nisko, Poland) dissolved tissue quicker during the first 35 minutes (P < .05). In this period, the weight loss with 10% Ca(OCl)2 differed from Chlorax at all time intervals except at 5 and 35 minutes (P < .05); 5% Ca(OCl)2 showed no significant differences with 10% Ca(OCl)2 and Tesco bleach (1.36% NaOCl) (Tesco Stores Ltd, Chestnut, UK) in the first 35 minutes except at the 5-minute measurement. Conclusions: Within the limitations of this study, Chlorax (4.65% NaOCl) dissolved tissue faster than the Ca(OCl)2 solutions and Tesco thin bleach (1.36% NaOCl) over the first 35 minutes, but there were no significant differences among the solutions thereafter.

Item Type: Article
Date Type: Published Online
Status: Published
Schools: Dentistry
Publisher: Elsevier
ISSN: 0099-2399
Last Modified: 23 Jan 2023 14:30

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