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Non-thionamide antithyroid drug options in Graves' hyperthyroidism

Ruslan, Aliya and Okosieme, Onyebuchi E. 2023. Non-thionamide antithyroid drug options in Graves' hyperthyroidism. Expert Review of Endocrinology and Metabolism 18 (1) , pp. 67-79. 10.1080/17446651.2023.2167709

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The thionamide anti-thyroid drugs namely carbimazole, methimazole, and propylthiouracil, have been the predominant therapy modality for Graves’ hyperthyroidism for over 60 years. Although these agents have proven efficacy and favorable side-effect profiles, non-thionamide alternatives are occasionally indicated in patients who are intolerant or unresponsive to thionamides alone. This review examines the available non-thionamide drug options for the control of Graves’ hyperthyroidism and summarizes their clinical utility, efficacy, and limitations.

Item Type: Article
Date Type: Published Online
Status: Published
Schools: Medicine
Publisher: Taylor and Francis Group
ISSN: 1744-6651
Date of First Compliant Deposit: 30 March 2023
Date of Acceptance: 9 January 2023
Last Modified: 05 Feb 2024 16:26

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