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Depression, anxiety, and stress among hangover-sensitive and hangover-resistant drinkers

Kim, Andy J., Merlo, Agnese, Mackus, Marlou, Bruce, Gillian, Johnson, Sean J., Alford, Chris, Sherry, Simon B., Stewart, Sherry H. and Verster, Joris C. 2023. Depression, anxiety, and stress among hangover-sensitive and hangover-resistant drinkers. Journal of Clinical Medicine 12 (8) , 2766. 10.3390/jcm12082766

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This study investigated potential differences in baseline (i.e., non-hangover-related) levels of depression, anxiety, and stress between individuals who are sensitive to and those resistant to hangovers after consuming alcohol. Participants included 5111 university students from the Netherlands and the U.K., including 3205 hangover-sensitive and 1906 hangover-resistant drinkers. All participants completed surveys on their demographics, alcohol consumption, and hangover susceptibility (whether they experienced a hangover in the past 12 months), as well as their baseline levels of depression, anxiety, and stress on the DASS-21 scale. The results showed that hangover-sensitive drinkers had significantly higher levels of anxiety and stress, but not depression, compared to hangover-resistant drinkers. However, the observed differences between the two groups were small, with a magnitude of less than 1 out of 42 points on the DASS-21 anxiety and stress subscales, and are thus unlikely to be clinically meaningful.

Item Type: Article
Date Type: Published Online
Status: Published
Schools: Medicine
Centre for Trials Research (CNTRR)
Additional Information: License information from Publisher: LICENSE 1: URL:, Type: open-access
Publisher: MDPI
ISSN: 2077-0383
Date of First Compliant Deposit: 9 May 2023
Date of Acceptance: 6 April 2023
Last Modified: 10 May 2023 10:00

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