Imaging standardisation in metastatic colorectal cancer: A joint EORTC-ESOI-ESGAR expert consensus recommendation

Unterrainer, Marcus, Deroose, Christophe M., Herrmann, Ken, Moehler, Markus, Blomqvist, Lennart, Cannella, Roberto, Caramella, Caroline, Caruso, Damiano, Chouhan, Manil D., Denecke, Timm, De la Pinta, Carolina, De Geus-Oei, Lioe-Fee, Dulskas, Audrius, Eisenblätter, Michel, Foley, Kieran G., Gourtsoyianni, Sofia, Lecouvet, Frederic E., Lopci, Egesta, Maas, Monique, Obmann, Markus M., Oprea-Lager, Daniela E., Verhoeff, Joost J.C., Santiago, Ines, Terraz, Sylvain, D'Anastasi, Melvin, Regge, Daniele, Laghi, Andrea, Beets-Tan, Regina G.H., Heinemann, Volker, Lordick, Florian, Smyth, Elizabeth C., Ricke, Jens and Kunz, Wolfgang G. 2022. Imaging standardisation in metastatic colorectal cancer: A joint EORTC-ESOI-ESGAR expert consensus recommendation. European Journal of Cancer 176 , pp. 193-206. 10.1016/j.ejca.2022.09.012

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Abstract

Background Treatment monitoring in metastatic colorectal cancer (mCRC) relies on imaging to evaluate the tumour burden. Response Evaluation Criteria in Solid Tumors provide a framework on reporting and interpretation of imaging findings yet offer no guidance on a standardised imaging protocol tailored to patients with mCRC. Imaging protocol heterogeneity remains a challenge for the reproducibility of conventional imaging end-points and is an obstacle for research on novel imaging end-points. Patients and methods Acknowledging the recently highlighted potential of radiomics and artificial intelligence tools as decision support for patient care in mCRC, a multidisciplinary, international and expert panel of imaging specialists was formed to find consensus on mCRC imaging protocols using the Delphi method. Results Under the guidance of the European Organisation for Research and Treatment of Cancer (EORTC) Imaging and Gastrointestinal Tract Cancer Groups, the European Society of Oncologic Imaging (ESOI) and the European Society of Gastrointestinal and Abdominal Radiology (ESGAR), the EORTC-ESOI-ESGAR core imaging protocol was identified. Conclusion This consensus protocol attempts to promote standardisation and to diminish variations in patient preparation, scan acquisition and scan reconstruction. We anticipate that this standardisation will increase reproducibility of radiomics and artificial intelligence studies and serve as a catalyst for future research on imaging end-points. For ongoing and future mCRC trials, we encourage principal investigators to support the dissemination of these imaging standards across recruiting centres.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Publisher:	Elsevier
ISSN:	0959-8049
Date of First Compliant Deposit:	10 May 2023
Date of Acceptance:	22 September 2022
Last Modified:	12 May 2023 16:55
URI:	https://orca.cardiff.ac.uk/id/eprint/159363

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