Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

MTG570 AposHealth for osteoarthritis (OA) of the knee: External Assessment Group report

O'Connell, Susan, Dale, Megan, Bird, Samuel, Rahim, Ayesha, Willis, Simone ORCID: and Morris, Rhys 2022. MTG570 AposHealth for osteoarthritis (OA) of the knee: External Assessment Group report. [Project Report]. NICE. Available at:

[thumbnail of supporting-documentation.pdf]
PDF - Published Version
Download (6MB) | Preview


AposHealth (previously AposTherapy) is a non-invasive device worn on the foot to adjust the gait of the user to improve symptoms of knee osteoarthritis (OA), a condition that results in joints becoming stiff and painful. It is proposed as an addition to non-surgical standard care, or as an alternative. The comparators included alternative devices such as supports, splints and braces or intra-articular corticosteroid injections. Clinical evidence primarily from low quality non-comparative, observational studies indicates that users of AposHealth experience improvements in symptoms of knee OA including pain, function and stiffness. Quality of life outcomes also show improvements and both clinical and patient experts supported these findings from their own experience. Two comparative studies, one high quality randomised trial and one prospective comparative study, did report improvements with AposHealth however both studies compared with a sham device rather than standard care. There is a lack of evidence comparing AposHealth to non-surgical standard care treatment options such as manual therapy, walking aids, and intra-articular corticosteroid injections and their respective impacts on pain and function. Additionally, there is a lack of evidence relating to the outcome of TKR surgery delay or avoidance and in general there is a lack of long-term follow-up data (beyond 2 years). This is a key gap in the evidence and has a particular impact on the economic assessment.

Item Type: Monograph (Project Report)
Date Type: Publication
Status: Published
Schools: Academic & Student Support Service
Publisher: NICE
Date of First Compliant Deposit: 17 November 2023
Last Modified: 01 Dec 2023 15:35

Actions (repository staff only)

Edit Item Edit Item


Downloads per month over past year

View more statistics