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Further refinement of the Patient-Reported Impact of Dermatological Diseases (PRIDD) measure using classical test theory and item response theory

Pattinson, Rachael ORCID:, Trialonis-Suthakharan, Nirohshah, Pickles, Timothy ORCID:, Austin, Jennifer, FitzGerald, Allison, Augustin, Matthias and Bundy, Edna ORCID: 2024. Further refinement of the Patient-Reported Impact of Dermatological Diseases (PRIDD) measure using classical test theory and item response theory. British Journal of Dermatology 190 (5) , pp. 718-728. 10.1093/bjd/ljad487

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Background: Existing dermatology-specific patient-reported outcome measures (PROMs) do not fully capture the substantial physical, psychological, and social impact of dermatological conditions on patients’ lives and are not recommended for use according to the Consensus-based Standards for the Selection of Health Measurement Instruments (COSMIN) criteria. Most were developed with insufficient patient involvement and relied on classical psychometric methods. We are developing the new Patient-Reported Impact of Dermatological diseases (PRIDD) measure for use in research and clinical practice in partnership with patients. Objectives: To examine the factor structure of PRIDD, determine the definitive selection of items for each subscale, and establish structural validity and internal consistency through classical and modern psychometric methods. Methods: Two cross-sectional online surveys. Adults (≥ 18 years) worldwide living with a dermatological condition were recruited through the International Alliance of Dermatology Patient Organizations’ (GlobalSkin) membership network. They completed PRIDD and a demographics questionnaire via an online survey. We examined missing data and distribution of scores for each item. The factor structure was assessed using confirmatory and exploratory factor analysis (Survey 1). Internal consistency was examined using Cronbach’s alpha. Rasch measurement theory analyses were conducted, including iterative assessment of rating scale function, fit to the Rasch model, unidimensionality, reliability, local dependence, targeting and differential item functioning (DIF)(Survey 1 and 2). Results: 483 and 504 people participated in Survey 1 and 2, respectively. All items had ≤3% missing scores and all five response options were used. A four-factor model showed best fit. PRIDD and all four subscales were internally consistent but showed some misfit to the Rasch measurement model. Adjustments were made to rectify disordered thresholds, remove misfitting items, local dependency and DIF, and improve targeting. The resultant 16-item version and subscales fit the Rasch model, showed no local dependency or DIF at the test level, and were well-targeted. Conclusions: This field test study produced the final PRIDD consisting of 16 items across four domains. The data triangulated and refined the conceptual framework of impact and provide evidence of PRIDD’s structural validity and internal consistency. The final step in PRIDD’s development and validation is to test the remaining measurement properties.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Healthcare Sciences
Centre for Trials Research (CNTRR)
Subjects: B Philosophy. Psychology. Religion > BF Psychology
R Medicine > RL Dermatology
Publisher: Oxford University Press
ISSN: 0007-0963
Funders: International Alliance of Dermatology Patient Organisations
Date of First Compliant Deposit: 18 December 2023
Date of Acceptance: 2 December 2023
Last Modified: 08 May 2024 16:43

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