Mohapatra, Debendra, Pradhan, Tapas ![]() |
Official URL: http://dx.doi.org/10.1055/s-0033-1340853
Abstract
The synthesis of Z-isomers of both the proposed and revised structures of aspergillide B is described. A divergent route is employed that involves kinetically controlled ring-closing metathesis for the construction of a 14-membered macrocyclic ring, ester formation under Yamaguchi conditions, a Wacker-type oxidative cyclization for creation of the C4 stereogenic center and a previously reported diastereoselective isomerization–iodocyclization strategy for the construction of the 2,6-trans-disubstituted tetrahydropyran subunit.
Item Type: | Article |
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Date Type: | Publication |
Status: | Published |
Schools: | Chemistry |
Publisher: | Thieme Gruppe |
ISSN: | 0039-7881 |
Date of Acceptance: | 3 February 2014 |
Last Modified: | 16 May 2024 01:40 |
URI: | https://orca.cardiff.ac.uk/id/eprint/165585 |
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