Koimtzis, Georgios, Geropoulos, Georgios, Chalklin, Christopher, Karniadakis, Ioannis, Szabo, Laszlo, Ilham, Mohammed Adel, Stephens, Michael, Asderakis, Argiris and Khalid, Usman
2024.
The influence of socioeconomic deprivation on outcomes in transplant patients infected with SARS-CoV-2 in Wales.
Clinical Transplantation
38
(1)
, e15245.
10.1111/ctr.15245
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Abstract
Introduction: SARS-CoV-2 infection has had a significant impact on vulnerable individuals including transplant patients. Socioeconomic deprivation negatively affects outcomes of many health conditions. The aim of this study was to evaluate the effect of socioeconomic deprivation on the incidence and severity of SARS-CoV-2 infection among Welsh transplant patients. Methods: This study is a retrospective, cross-sectional study on the transplant population of Wales. The Welsh Index of Multiple Deprivation (WIMD) was used to assess the influence of socioeconomic deprivation on outcomes of Welsh transplant patients who developed SARS-CoV-2 infection. Outcome measures were the incidence of SARS-CoV-2 infection, rates of hospital and ICU admission, development of acute kidney injury (AKI) and mortality. A logistic binomial regression analysis was used to correlate the various risk factors with the incidence of SARS-CoV-2 infection. Results: Two hundred and sixty-six (25%) of regular follow up patients had SARS-CoV-2 infection; of these 55 (20.7%) were admitted, 15 (5.6%) to ICU, 37 (13.9%) developed AKI, and 23 (8.6%) died. In a regression analysis, patients of younger age were associated with more (p = .001) and those with SPK (simultaneous pancreas kidney) transplant less chance of infection (p = .038), whereas social deprivation was not associated with the chance of infection (p = .14). In regression analysis increased social deprivation was associated with higher chance of AKI post SARS-CoV-2 (p = .049). Conclusions: Socioeconomic deprivation did not affect the rates or severity of SARS-CoV-2 infection apart from the degree of AKI in Welsh Transplant patients. Adherence to the preventive measures for this high-risk population must continue to remain a priority.
Item Type: | Article |
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Date Type: | Publication |
Status: | Published |
Schools: | Medicine |
Publisher: | Wiley-Blackwell |
ISSN: | 0902-0063 |
Date of First Compliant Deposit: | 9 April 2024 |
Date of Acceptance: | 8 January 2024 |
Last Modified: | 10 Nov 2024 17:15 |
URI: | https://orca.cardiff.ac.uk/id/eprint/167828 |
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