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Acanthamoeba keratitis: new hopes for potential interventions for a curable but often refractory disease

Alawfi, Bader Saleem, Khan, Naveed Ahmed, Lloyd, David ORCID: https://orcid.org/0000-0002-5656-0571 and Siddiqui, Ruqaiyyah 2024. Acanthamoeba keratitis: new hopes for potential interventions for a curable but often refractory disease. Expert Review of Ophthalmology 19 (4) , pp. 271-280. 10.1080/17469899.2024.2370881

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Abstract

Introduction Often associated with contact lens wear, Acanthamoeba keratitis is an extremely painful blinding infection that has remained significant despite advances in drug discovery and chemotherapies. Current treatment is intricate and demands early diagnosis, aggressive and prolonged application, and may result in infection recurrence. The latter is due to the ability of the parasite to undergo cellular differentiation and transform into a resistant cyst form or infective trophozoite form.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Biosciences
Publisher: Taylor and Francis Group
ISSN: 1746-9899
Date of Acceptance: 18 June 2024
Last Modified: 04 Sep 2024 12:28
URI: https://orca.cardiff.ac.uk/id/eprint/170052

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