Ureaplasma

Spiller, O. Brad ORCID: https://orcid.org/0000-0002-9117-6911 and Sweeney, Emma L. 2026. Ureaplasma. Gasparich, Gali, ed. Bergey's Manual of Systematics of Archaea and Bacteria, Wiley, (10.1002/9781118960608.gbm01264.pub4)

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Abstract

U.re.a.plas'ma. Chem. fem. n. urea, urea; Gr. neut. n. plasma, anything formed or moulded, image, figure, form; N.L. neut. n. Ureaplasma, urea form [probably better: Ureiplasma]. Mycoplasmatota / Mollicutes / Mycoplasmatales / Mycoplasmataceae / Ureaplasma Bacteria belonging to the genus Ureaplasma are small (100–800 nm in diameter), pleomorphic, lack a peptidoglycan cell wall, and are surrounded by a phospholipid bilayer membrane. Primarily coccoid in appearance, although coccobacillary and filamentous forms can also occur. These bacteria form exceptionally small (<0.2 mm) colonies on solid media. Similar to the closely related genus Mycoplasma, ureaplasmas have small (0.75–1.01 Mb) A+T-rich genomes, use the codon UGA to encode tryptophan, and are nutritionally fastidious, requiring exogenous sterols, polyamines, and peptides for axenic growth. Unlike mycoplasmas, ureaplasmas are incredibly unique as they hydrolyze urea for ATP synthesis instead of glucose or arginine. All species are commensals or opportunistic parasites of their vertebrate hosts. DNA G + C content (mol%): 25.4–36.8 (complete genome sequences). Type species: Ureaplasma urealyticum Shepard et al. 1974AL emend. Robertson et al. 2002.

Item Type:	Book Section
Date Type:	Published Online
Status:	Published
Schools:	Schools > Medicine
Publisher:	Wiley
ISBN:	9781118960608
Last Modified:	27 May 2026 08:49
URI:	https://orca.cardiff.ac.uk/id/eprint/186752

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