Evaluation of antithrombotic therapy following first presentation of stroke. A population-level observational cohort study in Wales [Abstract]

Harris, Daniel, Herbert, Laura and Hewitt, Jonathan ORCID: https://orcid.org/0000-0002-7924-1792 2026. Evaluation of antithrombotic therapy following first presentation of stroke. A population-level observational cohort study in Wales [Abstract]. European Stroke Journal 11 (Supp_1) 10.1093/esj/aakag023.1966

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Abstract

Background and aims: To assess the provision of antithrombotic therapy in the year following a first diagnosis of stroke, using a Wales wide databank. Methods: A retrospective observational cohort study using routine electronic health records of 52,400 incident stroke patients in Wales between 2010 and 2023 with at least one year follow-up. Stroke survivors were classified as ischaemic, haemorrhagic or unspecified and were assessed being prescribed either antiplatelet (AP), antitcoagulant (AC), both or none. A further analysis in patients with atrial fibrillation (AF) was also conducted. Results: In ischaemic stroke 67.5% were taking AP, 18.4% AC, 7.9% both and 6.1% none. In haemorrhagic stroke 19.2% AP, 10.4% AC, 2.8% Both and 68% none and in unspecified stroke 69.8% AP, 12.8% AT, 5.8% both and 11.6% none. In people with AF and ischaemic stroke 12.1% were taking AP, 68% AC, 16.6% both and 3.3% none. In AF and haemorrhagic stroke 13.1% AP, 44.1% AC, 9.2% both and 34.6% none and in AF and unspecified stroke 17.4% AP, 62.88% AC, 15.1% Both and 4.7% none. Conclusions: Approximately two thirds of ischaemic stroke survivors with and without AF appeared to be on the appropriate antithrombotic management. Antithrombotic management was far more varied in people with haemorrhagic or unspecified stroke. These data highlight both the benefits to be gained from better targeting of treatment, identified suboptimum prescribing of treatments proven to improve outcomes in post-stroke management.

Item Type:	Short Communication
Date Type:	Publication
Status:	Published
Schools:	Schools > Medicine
Additional Information:	12th European Stroke Organisation Conference, 6-8 May 2026, Maastricht, Netherlands
Publisher:	SAGE Publications
ISSN:	2396-9873
Date of Acceptance:	1 January 2026
Last Modified:	11 May 2026 11:32
URI:	https://orca.cardiff.ac.uk/id/eprint/186927

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