ESOC2026LB161 Evaluation of lipid and blood pressure management following first presentation of stroke. A population-level observational cohort study in Wales [Abstract]

Hewitt, Jonathan ORCID: https://orcid.org/0000-0002-7924-1792, King, Daniel and Harris, Daniel 2026. ESOC2026LB161 Evaluation of lipid and blood pressure management following first presentation of stroke. A population-level observational cohort study in Wales [Abstract]. European Stroke Journal 11 (S1) , i1034. 10.1093/esj/aakag023.1940

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Abstract

Background and aims To assess the effectiveness of blood pressure (BP) and lipid management in the year following a first diagnosis of stroke. Methods A retrospective observational cohort study using routine electronic health-records of 52,400 incident stroke patients with at least one year follow-up in Wales (2010-23), including 33,080 ischaemic strokes (IS), 4,403 haemorrhagic stroke (HS) and 14,920 unspecified strokes (US) with at least one year follow-up in Wales (2010-23). Results Altogether, 17% of IS patients, 59% of HS and 23% of US were not prescribed any lipid lowering therapy (LLT) in the year post stroke. Only 22% of IS, 9% of HS and 20% of US had a documented LDL-C <1.8mmol/L. In multivariable regression analyses, a history of diabetes and prescription of LLT were independently associated with a greater likelihood of a documented LDL-C level; male sex and LLT were associated with a higher likelihood of documentation of LDL-C <1.8mmol/L. Overall, 84% ,79% and 85% of IS, HS and US patients respectively, had BP documented in their primary care record and 67%, 64% and 67% had a documented BP <140/90mmHg in the year following their stroke. Prescription for antihypertensives and history of diabetes mellitus were independently associated with a greater likelihood of a documented BP in the year following diagnosis in multivariable regression analyses. Conclusions Testing, treatment and control of lipids and blood pressure were suboptimal amongst these very high-risk patients. These data show significant opportunity for improving secondary prevention of stroke in this high risk population. Conflict of interest

Item Type:	Short Communication
Date Type:	Publication
Status:	Published
Schools:	Schools > Medicine
Additional Information:	License information from Publisher: LICENSE 1: URL: https://creativecommons.org/licenses/by-nc/4.0/, Start Date: 2026-05-06
Publisher:	Oxford University Press
ISSN:	2396-9873
Date of First Compliant Deposit:	21 May 2026
Date of Acceptance:	1 January 2026
Last Modified:	21 May 2026 11:45
URI:	https://orca.cardiff.ac.uk/id/eprint/187164

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