Millington, George W.M., Patel, Priya U., Chua, Ser-Ling, Bewley, Anthony, Sterling, Jane C., Hughes, Jenny R., Papanikolaou, Marieta, Bhatti, Kash, Thompson, Andrew R.  ORCID: https://orcid.org/0000-0001-6788-7222, Hashme, Maria, Wang, Chenxi, Mohd Mustapa, M Firouz, Exton, Lesley S. and Mansour Kiaee, Zahra
2026.
British Association of Dermatologists living guideline for managing people with nodular prurigo (prurigo nodularis) 2025.
British Journal of Dermatology
194
(6)
, pp. 1035-1045.
10.1093/bjd/ljag070
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Abstract
Nodular prurigo (NP) is a chronic skin condition. Lesions can be either single or widespread on the body. Thus, it can have a negative impact on a person’s quality of life. The exact cause of NP is unknown, as several mechanisms play a role. These mechanisms sometimes overlap between physical and brain–behavioural elements. Dermatologists diagnose NP based on a history of long-lasting itching and scratching. A Guideline Development Group met to produce a new guideline for treating people with NP. The group included consultant dermatologists, a psychotherapist, dermatology trainees, a general practitioner and people with lived experience of NP. The group identified and reviewed the current literature on treating NP. They discussed the findings at length before producing a set of recommendations. The guideline will provide up-to-date management guidance for healthcare practitioners. Initial steps included taking a full history and examination of patients. This included causes of itch, patient education and reversing the itch–scratch habit. The first treatment option is usually topical therapy (applied to the skin). If this fails, other options include phototherapy and oral medications. Further treatments include nonsedating antihistamines and low-dose antidepressants. Steroid injections or cryotherapy (freezing with liquid nitrogen) are options for single lesions.
| Item Type: | Article |
|---|---|
| Date Type: | Publication |
| Status: | Published |
| Schools: | Schools > Psychology |
| Additional Information: | RRS policy applied |
| Publisher: | Wiley-Blackwell |
| ISSN: | 0007-0963 |
| Date of First Compliant Deposit: | 8 June 2026 |
| Date of Acceptance: | 20 February 2026 |
| Last Modified: | 08 Jun 2026 09:15 |
| URI: | https://orca.cardiff.ac.uk/id/eprint/187325 |
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