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Massive pleural effusion and marked increase of CA-125

Hussain, S. F., Grayez, J., Grigorian, A. and Green, John T. 2004. Massive pleural effusion and marked increase of CA-125. Postgraduate Medical Journal 80 (943) , pp. 300-301. 10.1136/pgmj.2003.012377

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Abstract

The tumour associated CA-125 antigen is widely used in monitoring ovarian carcinoma. In women with a massive pleural effusion and ascites, markedly increased CA-125 levels may lead to an erroneous diagnosis of ovarian cancer. Very high levels of tumour markers may be present in patients with benign pleural effusion, ascites, and chronic liver disease. Raised levels of tumour markers in serum or pleural fluid, in the absence of positive cytology, should be interpreted with caution.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Schools > Medicine
Publisher: Oxford University Press
ISSN: 0032-5473
Date of Acceptance: 19 August 2003
Last Modified: 11 Aug 2026 13:45
URI: https://orca.cardiff.ac.uk/id/eprint/188910

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