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Neuropeptide Y signalling on hippocampal stem cells in health and disease

Gray, William Peter ORCID: 2008. Neuropeptide Y signalling on hippocampal stem cells in health and disease. Molecular and Cellular Endocrinology 288 (1-2) , pp. 52-62. 10.1016/j.mce.2008.02.021

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Neuropeptides are emerging as key components in the hippocampal neurogenic niche in health and disease, regulating many aspects of neurogenesis and the synaptic integration of newly generated neurons. This review focuses on the role of neuropeptide Y in the control of stem/precursor cells in the postnatal and adult hippocampus. It is likely that neuropeptide Y releasing interneurons are key sensors of neural activity, modulating neurogenesis appropriately. This is likely to be a fruitful area of research for extending our understanding of the control of stem cells in the normal and diseased brain.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Biosciences
Subjects: R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Uncontrolled Keywords: NPY; Stem cell; Hippocampus; Neurogenesis; Interneuron; Learning and memory; Mood
Additional Information: Available online 2 March 2008.
Publisher: Elsevier
ISSN: 0303-7207
Related URLs:
Last Modified: 19 Oct 2022 09:11

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