CDP-choline: repeated oral dose tolerance studies in adult healthy volunteers

Dinsdale, J. R., Griffiths, G. K., Castello, J., Maddock, J., Ortiz, J. A. and Aylward, Mansel 1983. CDP-choline: repeated oral dose tolerance studies in adult healthy volunteers. Fortschritte der Arzneimittelforschung Progress in Drug Research Progres des Recherches Pharmaceutiques 33 (7A) , pp. 1061-1065.

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Abstract

Cytidine diphosphate choline (CDP-choline, citicoline, Somazina) was administered to 12 adult healthy volunteer subjects in two short-term chronic oral dose regimens (600 mg X day-1 and 1g X day-1), each of 5 consecutive days, and compared with a corresponding regimen of matched placebo. Transient headaches were the only untoward events recorded, occurring in 4 and 5 subjects, respectively, on the lower and higher dose regimens but in only one subject during placebo administration.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Subjects:	R Medicine > R Medicine (General) R Medicine > RM Therapeutics. Pharmacology
Publisher:	Springer Verlag
ISSN:	0071-786X
Last Modified:	04 Jun 2017 04:18
URI:	https://orca.cardiff.ac.uk/id/eprint/36537

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