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CDP-choline: repeated oral dose tolerance studies in adult healthy volunteers

Dinsdale, J. R., Griffiths, G. K., Castello, J., Maddock, J., Ortiz, J. A. and Aylward, Mansel 1983. CDP-choline: repeated oral dose tolerance studies in adult healthy volunteers. Fortschritte der Arzneimittelforschung Progress in Drug Research Progres des Recherches Pharmaceutiques 33 (7A) , pp. 1061-1065.

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Cytidine diphosphate choline (CDP-choline, citicoline, Somazina) was administered to 12 adult healthy volunteer subjects in two short-term chronic oral dose regimens (600 mg X day-1 and 1g X day-1), each of 5 consecutive days, and compared with a corresponding regimen of matched placebo. Transient headaches were the only untoward events recorded, occurring in 4 and 5 subjects, respectively, on the lower and higher dose regimens but in only one subject during placebo administration.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Subjects: R Medicine > R Medicine (General)
R Medicine > RM Therapeutics. Pharmacology
Publisher: Springer Verlag
ISSN: 0071-786X
Last Modified: 04 Jun 2017 04:18

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