Kamudoni, Paul, Salek, Mir-saeed, Mueller, B. and Mueller, C. 2012. Hyperhidrosis Quality of Life Index (Hidroqol (c)): a novel patient reported outcome measure in hyperhidrosis [Abstract]. Journal of Investigative Dermatology 132 (S2) , S73. 10.1038/jid.2012.300 |
Abstract
The aim of this study was to develop and validate a disease-specific health-related quality of life (HRQoL) instrument for use in hyperhidrosis. Internet focus groups (n=9), semi-structured interviews (n=32) and an online survey (n=30) were carried out with patients recruited from sixteen online social networking sites related to hyperhidrosis. Nvivo8 software was used for the content analysis of data transcripts. Panel discussions with dermatologist (n=5) and patients (n=7) were conducted to assess content validity of the draft questionnaire. Seventy-one patients (M=21; F=50; median age=31.5; range=16–67 years) took part in the study. Median disease duration was 21 years (3–60 years). Twenty-nine themes (aggregating 94 HRQoL issues) were identified. A selection of the most common themes included: lifestyle impacts (n=54); negative emotions (49); difficulties with physical contact (47); concerns over people's judgement (46); trouble with work tasks (45); interaction with others (41); self-image (35); personal relationships (28). The patients-panel strongly agreed on all aspects of the questionnaire evaluated i.e. Gwet's AC1 agreement coefficient was >0.7. The dermatologist-panel had slight agreement on language clarity (0.2) and moderate to strong agreement on language clarity (0.5), completeness (0.6) and scaling (1.0). This study has identified major HRQoL issues that patients with hyperhidrosis face, which were in turn used as content for the development of the new questionnaire. Expert panel ratings supported the content validity of the Hidroqol©. Further development of the new instrument will involve the application of classical test theory and item response theory to evaluate its psychometric properties.
Item Type: | Article |
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Date Type: | Publication |
Status: | Published |
Schools: | Pharmacy |
Subjects: | R Medicine > RM Therapeutics. Pharmacology |
Publisher: | Nature Publishing Group |
ISSN: | 0022-202X |
Last Modified: | 08 Feb 2022 12:00 |
URI: | https://orca.cardiff.ac.uk/id/eprint/41041 |
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