Angell, Annette 2005. The design, synthesis and evaluation of some novel antiviral nucleosides. PhD Thesis, Cardiff University. |
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Abstract
An investigation into the pH stability of the BCNAs was also carried out and the parent analogue bearing a pentyphenyl side chain was found to be stable at a range of pHs. Finally, with the X-ray crystal structure of VZV thymidine kinase published we began a preliminary investigation into the possible interaction the BCNAs with this enzyme using molecular modelling
Item Type: | Thesis (PhD) |
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Status: | Unpublished |
Schools: | Pharmacy |
Subjects: | R Medicine > RM Therapeutics. Pharmacology |
Date of First Compliant Deposit: | 30 March 2016 |
Last Modified: | 05 Jul 2022 13:12 |
URI: | https://orca.cardiff.ac.uk/id/eprint/55384 |
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