Molecular and cellular basis of cancer invasion and metastasis: Implications for treatment

Jiang, Wen Guo ORCID: https://orcid.org/0000-0002-3283-1111, Puntis, M. C. A. and Hallett, Maurice Bartlett ORCID: https://orcid.org/0000-0001-8197-834X 1994. Molecular and cellular basis of cancer invasion and metastasis: Implications for treatment. British Journal of Surgery 81 (11) , pp. 1576-1590. 10.1002/bjs.1800811107

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Abstract

In the past decade significant advances in establishing the underlying biological mechanisms of tumour invasion and metastasis have been made. Some of the triggering factors and genes relevant to metastatic spread have been identified. Advances have also been made in understanding the signal transduction pathways involved in invasion and metastasis. This increased comprehension of the malignant metastatic process has enabled new antimetastatic strategies to be devised. This review summarizes progress in these areas and discusses the implications for the treatment of metastasis.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Subjects:	R Medicine > R Medicine (General)
Publisher:	Wiley-Blackwell
ISSN:	0007-1323
Last Modified:	28 Oct 2022 09:01
URI:	https://orca.cardiff.ac.uk/id/eprint/73009

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