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Development of the Huntington disease work function scale

Brossman, Bradley, Williams, Janet K., Downing, Nancy, Mills, James A., Paulsen, Jane S., Price, Kathleen and Rosser, Anne ORCID: 2012. Development of the Huntington disease work function scale. Journal of Occupational and Environmental Medicine 54 (10) , pp. 1300-1308. 10.1097/JOM.0b013e31825f30ab

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OBJECTIVE: A work function measure specific for persons with prodromal Huntington disease (HD) was created to assist with workplace accommodations. METHODS: A self-report HD Work Function (HDWF) measure was developed from focus group and expert validation. RESULTS: Pilot studies with 238 people with prodromal HD, and 185 companions; and 89 people without prodromal HD, and 70 companions indicate that HDWF has acceptable internal consistency (Cronbach α = 0.77), acceptable interrater reliability (r = 0.58), and acceptable convergent validity with selected items from the Endicott Work Productivity Scale (r = -0.56), Social Adjustment Scale-Self Report (r = -0.29), and Everyday Cognition (r = -0.70). The HDWF can distinguish between people with prodromal HD and people with an HD family history who do not have prodromal HD (P < 0.0001). CONCLUSIONS: The HDWF is a brief self-assessment that may be used to monitor work function.

Item Type: Article
Date Type: Publication
Status: Published
Schools: MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG)
Neuroscience and Mental Health Research Institute (NMHRI)
Subjects: R Medicine > R Medicine (General)
Additional Information: Kathleen Price and Anne Rosser are collaborators on this article.
Publisher: Lippincott Williams & Wilkins
ISSN: 1076-2752
Last Modified: 28 Oct 2022 10:39

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