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Development of a technique for recording the focal rod ERG

Binns, Alison and Margrain, Thomas Hengist ORCID: 2006. Development of a technique for recording the focal rod ERG. Ophtalmic and physiological optics 26 (1) , pp. 71-79. 10.1111/j.1475-1313.2005.00355.x

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The scotopic ERG recorded in response to a focal stimulus has a double b-wave. The first wave results from direct focal stimulation of the retina, and the second originates in the peripheral retina in response to scattered light. The aim of this study was to assess two possible protocols for the isolation of the focal rod response, namely 'Subtraction' and 'Background Adaptation' techniques. The Subtraction technique involved the recording of a full-field response, which matched the b-wave elicited by intraocular light scatter, and the subtraction of this full-field response from the initial trace to isolate the focal component. In the Background Adaptation technique an adapting surround was used to suppress the response from the peripheral retina. Focal rod responses were isolated with both techniques. However, the Background Adaptation technique was found to more reliably elicit a focal response with a measurable a-wave, and was also considerably less time consuming than the Subtraction technique.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Optometry and Vision Sciences
Uncontrolled Keywords: Background adaptation ; Electroretinogram ; Scotopic ; Subtraction
Publisher: College of Optometrists
ISSN: 02755408
Last Modified: 17 Oct 2022 08:41

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