Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

DNA pooling as a tool for large-scale association studies in complex traits

Norton, Nadine, Williams, Nigel Melville ORCID: https://orcid.org/0000-0003-1177-6931, O'Donovan, Michael Conlon ORCID: https://orcid.org/0000-0001-7073-2379 and Owen, Michael John ORCID: https://orcid.org/0000-0003-4798-0862 2004. DNA pooling as a tool for large-scale association studies in complex traits. Annals of Medicine 36 (2) , pp. 146-152. 10.1080/07853890310021724

Full text not available from this repository.

Abstract

Pooled genotyping is a powerful and efficient tool for high throughput association analysis, both case-control and family-based. The use of pooling designs can significantly reduce the consumable and labour costs of a study. At the same time, since it is also extremely efficient with DNA resources, pooling can be an extremely effective method for conserving DNA. Here, we consider the main points in study design, and illustrate the application of pooling using psychiatric phenotypes as an example.

Item Type: Article
Date Type: Publication
Status: Published
Schools: MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG)
Medicine
Neuroscience and Mental Health Research Institute (NMHRI)
Subjects: R Medicine > R Medicine (General)
Publisher: Informa Healthcare
ISSN: 0785-3890
Last Modified: 17 Jul 2023 06:48
URI: https://orca.cardiff.ac.uk/id/eprint/81789

Citation Data

Cited 64 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item Edit Item