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Combined EEG-fMRI and tractography to visualise propagation of epileptic activity

Hamandi, Khalid, Powell, H W R, Laufs, H, Symms, M R, Barker, G J, Parker, G J M, Lemieux, L and Duncan, J S 2008. Combined EEG-fMRI and tractography to visualise propagation of epileptic activity. Journal of Neurology, Neurosurgery & Psychiatry 79 (5) , pp. 594-597. 10.1136/jnnp.2007.125401

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In a patient with refractory temporal lobe epilepsy, EEG-fMRI showed activation in association with left anterior temporal interictal discharges, in the left temporal, parietal and occipital lobes. Dynamic causal modelling suggested propagation of neural activity from the temporal focus to the area of occipital activation. Tractography showed connections from the site of temporal lobe activation to the site of occipital activation. This demonstrates the principle of combining EEG-fMRI and tractography to delineate the pathways of propagation of epileptic activity.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG)
Subjects: R Medicine > R Medicine (General)
Publisher: BMJ Publishing Group
ISSN: 0022-3050
Last Modified: 04 Jun 2017 08:41

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