The psychological burden of skin diseases: a cross-sectional multicenter study among dermatological out-patients in 13 European countries

Dalgard, Florence J., Gieler, Uwe, Tomas-Aragones, Lucia, Lien, Lars, Poot, Francoise, Jemec, Gregor B.E., Misery, Laurent, Szabo, Csanad, Linder, Dennis, Sampogna, Francesca, Evers, Andrea W.M., Halvorsen, Jon Anders, Balieva, Flora, Szepietowski, Jacek, Romanov, Dmitry, Marron, Servando E., Altunay, Ilknur K., Finlay, Andrew Yule ORCID: https://orcid.org/0000-0003-2143-1646, Salek, Sam S. and Kupfer, Jörg 2015. The psychological burden of skin diseases: a cross-sectional multicenter study among dermatological out-patients in 13 European countries. Journal of Investigative Dermatology 135 (4) , pp. 984-991. 10.1038/jid.2014.530

Preview

PDF - Accepted Post-Print Version Download (233kB) | Preview

Abstract

The contribution of psychological disorders to the burden of skin disease has been poorly explored, and this is a large-scale study to ascertain the association between depression, anxiety, and suicidal ideation with various dermatological diagnoses. This international multicenter observational cross-sectional study was conducted in 13 European countries. In each dermatology clinic, 250 consecutive adult out-patients were recruited to complete a questionnaire, reporting socio-demographic information, negative life events, and suicidal ideation; depression and anxiety were assessed with the Hospital Anxiety and Depression Scale. A clinical examination was performed. A control group was recruited among hospital employees. There were 4,994 participants––3,635 patients and 1,359 controls. Clinical depression was present in 10.1% patients (controls 4.3%, odds ratio (OR) 2.40 (1.67–3.47)). Clinical anxiety was present in 17.2% (controls 11.1%, OR 2.18 (1.68–2.82)). Suicidal ideation was reported by 12.7% of all patients (controls 8.3%, OR 1.94 (1.33–2.82)). For individual diagnoses, only patients with psoriasis had significant association with suicidal ideation. The association with depression and anxiety was highest for patients with psoriasis, atopic dermatitis, hand eczema, and leg ulcers. These results identify a major additional burden of skin disease and have important clinical implications.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Subjects:	R Medicine > R Medicine (General) R Medicine > RL Dermatology
Publisher:	Nature Publishing Group
ISSN:	0022-202X
Date of First Compliant Deposit:	12 February 2018
Date of Acceptance:	21 November 2014
Last Modified:	25 Nov 2023 12:43
URI:	https://orca.cardiff.ac.uk/id/eprint/84757

Citation Data

Cited 463 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item