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Bioreactivity of municipal solid waste landfill leachates-Hormesis and DNA damage

Koshy, Lata, Jones, Timothy Peter and Berube, Kelly Ann 2008. Bioreactivity of municipal solid waste landfill leachates-Hormesis and DNA damage. Water Research 42 (8-9) , pp. 2177-2183. 10.1016/j.watres.2007.11.030

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The issue of domestic waste is recognised as one of the most serious environmental problems facing the nation. With the UK producing 35 million tonnes of municipal solid waste per annum, an understanding of the ranges of toxicity of landfill emissions is crucial to determine the degree of concern we should have about the potential effects these waste sites could have upon nearby populations and the surrounding environment. The aim of this study was to evaluate the bioreactivity of landfill leachates in terms of their capacity to damage ROS-sensitive bacteriophage plasmid DNA and induce toxicity in a commercial photobacterium toxicity assay, based on the light emission of Vibrio fischeri bacteria (ROTAS™). The bacterial assay revealed widespread biostimulation and a hormesis response in the bacteria, with α-, β- and γ-response curves observed following exposure to the different landfill leachates. Different biological mechanisms lead to variations in bioreactivity, as seen in the plasmid DNA scission and ROTAS assays.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Biosciences
Earth and Environmental Sciences
Subjects: Q Science > QR Microbiology
Uncontrolled Keywords: Vibrio fischeri; Plasmid scission assay; Hormesis; Landfill leachate; Toxicity; Bioassay
Publisher: Elsevier
ISSN: 0043-1354
Last Modified: 02 Feb 2022 08:36

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