Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Alzheimer's disease: the amyloid hypothesis on trial

Harrison, Judith ORCID: and Owen, Michael John ORCID: 2016. Alzheimer's disease: the amyloid hypothesis on trial. British Journal of Psychiatry 208 (1) , pp. 1-3. 10.1192/bjp.bp.115.167569

[thumbnail of Alzheimer.pdf]
PDF - Accepted Post-Print Version
Download (146kB) | Preview


The pathogenesis of Alzheimer's disease is complex. The amyloid hypothesis has directed research efforts for many years, but it has recently been questioned after failed drug trials. Here, we review the evidence for and against and suggest that it might be premature to abandon the amyloid hypothesis.

Item Type: Article
Date Type: Publication
Status: Published
Schools: MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG)
Neuroscience and Mental Health Research Institute (NMHRI)
Subjects: R Medicine > R Medicine (General)
Publisher: Royal College of Psychiatrists
ISSN: 0007-1250
Date of First Compliant Deposit: 10 October 2018
Date of Acceptance: 21 July 2015
Last Modified: 12 Nov 2023 17:09

Citation Data

Cited 56 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item Edit Item


Downloads per month over past year

View more statistics