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Microbead models in glaucoma

Morgan, James Edwards ORCID: and Tribble, James R. 2015. Microbead models in glaucoma. Experimental Eye Research 141 , pp. 9-14. 10.1016/j.exer.2015.06.020

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The sustained and moderate elevation of intraocular pressure, which can be initiated at precise time points, remains the cornerstone of research into the mechanisms of glaucomatous retinal damage. We focus on the use of microbeads to block the outflow of aqueous following anterior chamber injection in a range of animals (mouse, rat and primate). We describe some of the most commonly used parameters and present guidance on injection technique and bead manipulation to facilitate the successful generation of experimental glaucoma.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Optometry and Vision Sciences
Subjects: R Medicine > RE Ophthalmology
Uncontrolled Keywords: Glaucoma; Microbead; Animal model; Rodent; Primate
Publisher: Elsevier
Funders: BBSRC
Date of First Compliant Deposit: 26 April 2016
Date of Acceptance: 23 June 2015
Last Modified: 06 Nov 2023 23:44

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