The SCALOP Trial Plan Assessment Form (PAF) as a tool for Radiation Therapy Trials Quality Assurance (RTTQA)

Nixon, Lisette Sheena ORCID: https://orcid.org/0000-0002-1270-6970, Mukherjee, S., Wills, L., Millin, T., Bridges, Sarah ORCID: https://orcid.org/0000-0002-7665-5770, Abrams, R. A., Joseph, G., Griffiths, G., Hurt, Chris Nicholas ORCID: https://orcid.org/0000-0003-1206-8355 and Staffurth, John Nicholas ORCID: https://orcid.org/0000-0002-7834-3172 2013. The SCALOP Trial Plan Assessment Form (PAF) as a tool for Radiation Therapy Trials Quality Assurance (RTTQA). International Journal of Radiation Oncology*Biology*Physics 87 (2) , S306. 10.1016/j.ijrobp.2013.06.804

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Abstract

SCALOP, a randomized Phase II multicenter trial, compared gemcitabine-chemoradiation (CRT) and capecitabine-CRT following induction chemotherapy in locally advanced pancreatic cancer (LAPC); 74 patients were randomized to a CRT arm. A prospective RTTQA program to ensure protocol compliance and high quality RT delivery involved: (1) RT trial protocol including radiologist outlined example images; (2) Centrally reviewed benchmark case for outlining and planning; (3) Real time, on-trial assessment of RT planning compliance for every patient using a trial specific PAF, to allow all planning data to be compared against protocol standards.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Biosciences Medicine
Subjects:	R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer)
Additional Information:	Supplement 1. Proceedings of the American Society for Radiation Oncology 55th Annual Meeting. ASTRO's 55th Annual Metting
Publisher:	Elsevier
ISSN:	0360-3016
Funders:	CRUK
Last Modified:	01 Nov 2022 10:06
URI:	https://orca.cardiff.ac.uk/id/eprint/90239

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