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The genetics of neuroticism and human values

Zacharopoulos, George, Lancaster, Thomas ORCID:, Maio, Gregory ORCID: and Linden, David ORCID: 2016. The genetics of neuroticism and human values. Genes, Brain and Behavior 15 (4) , pp. 361-366. 10.1111/gbb.12286

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Human values and personality have been shown to share genetic variance in twin studies. However, there is a lack of evidence about the genetic components of this association. This study examined the interplay between genes, values and personality in the case of neuroticism, because polygenic scores were available for this personality trait. First, we replicated prior evidence of a positive association between the polygenic neuroticism score (PNS) and neuroticism. Second, we found that the PNS was significantly associated with the whole human value space in a sinusoidal waveform that was consistent with Schwartz's circular model of human values. These results suggest that it is useful to consider human values in the analyses of genetic contributions to personality traits. They also pave the way for an investigation of the biological mechanisms contributing to human value orientations.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Psychology
Publisher: Wiley-Blackwell
ISSN: 1601-1848
Funders: MRC
Date of First Compliant Deposit: 15 June 2016
Date of Acceptance: 21 February 2016
Last Modified: 04 May 2023 23:49

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