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Childhood hyperactivity and mood problems at mid-life: evidence from a prospective birth cohort

Stuart-Smith, Jenny, Thapar, Anita ORCID:, Maughan, Barbara, Thapar, Ajay ORCID: and Collishaw, Stephan ORCID: 2017. Childhood hyperactivity and mood problems at mid-life: evidence from a prospective birth cohort. Social Psychiatry and Psychiatric Epidemiology 52 (1) , pp. 87-94. 10.1007/s00127-016-1285-5

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Purpose Childhood hyperactivity leads to mental health problems, but it is not known whether there are long-term risks for adult mood problems in unselected population cohorts that extend to mid-life. Aims were to examine links between childhood hyperactivity and mood problems up to age 50 years and to consider confounding factors and gender differences in associations. Methods The National Child Development Study (NCDS) is a UK cohort of children born in 1958. Children with (N = 453) and without (N = 9192) pervasive and persistent hyperactivity were followed to age 50. Adult mood was assessed using the Malaise Inventory at ages 23, 33, 42, and 50 years and the CIS-R interview at 45 years. Results Childhood hyperactivity predicted low mood at all adult assessments (ES = 0.27–0.45), including after covariate adjustment (childhood adversity, emotional and behavioural problems, and attainment). Conclusion Hyperactivity has enduring risk effects on low mood throughout the life course that extend to middle age.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG)
Subjects: R Medicine > R Medicine (General)
Uncontrolled Keywords: Hyperactivity; ADHD; Depression; Mood; Life course; Prospective
Publisher: Springer Verlag
ISSN: 0933-7954
Date of First Compliant Deposit: 30 September 2016
Date of Acceptance: 14 September 2016
Last Modified: 07 Nov 2023 23:44

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