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A novel method for the synthesis of 1-aryltetrahydroisoquinolines

Ghanim, Amany, Knight, David William, Rutkowski, Piotr, Osman, Nermine A., Abdel-Fattah, Hanan A. and Kadry, Azza M. 2017. A novel method for the synthesis of 1-aryltetrahydroisoquinolines. Tetrahedron Letters 58 (4) , pp. 294-297. 10.1016/j.tetlet.2016.11.115

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Carbenium ions generated from substituted benzhydryls using acid catalysis undergo smooth intramolecular trapping by pendant sulfonamide groups to provide excellent yields of 1-aryltetrahydroisoquinolines.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Chemistry
Subjects: Q Science > QD Chemistry
Uncontrolled Keywords: 1-Aryltetrahydroisoquinolines; Carbenium ions; Trapping; Intramolecular; Acid-catalysed
Publisher: Elsevier
ISSN: 0040-4039
Funders: Ministry of Higher Education in Egypt
Date of First Compliant Deposit: 23 January 2017
Date of Acceptance: 28 November 2016
Last Modified: 07 Nov 2023 02:15

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