ORCA
Online Research @ Cardiff

Clear Cookie - decide language by browser settings

Browse by All Cardiff Authors

Number of items: 58.

Bowden, Paul Edward 2011. Gene therapy for keratin genodermatoses: striving forward but obstacles persist. Journal of Investigative Dermatology 131 (7) , pp. 1403-1405. 10.1038/jid.2011.121

Bowden, Paul Edward 2011. Peeling skin syndrome: genetic defects in late terminal differentiation of the epidermis. Journal of Investigative Dermatology 131 (3) , pp. 561-564. 10.1038/jid.2010.434

Foster, A. P., Skuse, A. M., Higgins, R. J., Barrett, D. C., Philbey, A. W., Thomson, J. R., Thompson, H., Fraser, M. A., Bowden, Paul Edward and Day, M. J. 2010. Epidermolysis bullosa in calves in the United Kingdom. Journal of Comparative Pathology 142 (4) , pp. 336-340. 10.1016/j.jcpa.2009.10.001

Chamcheu, J. C., Virtanen, M., Navsaria, H., Bowden, Paul Edward, Vahlquist, A. and Törmä, H. 2010. Epidermolysis bullosa simplex due toKRT5mutations: mutation-related differences in cellular fragility and the protective effects of trimethylamineN-oxide in cultured primary keratinocytes. British Journal of Dermatology 162 (5) , pp. 980-989. 10.1111/j.1365-2133.2009.09615.x

Bowden, Paul Edward 2010. Mutations in a keratin 6 isomer (K6c) cause a type of focal palmoplantar keratoderma. Journal of Investigative Dermatology 130 (2) , pp. 336-338. 10.1038/jid.2009.395

Bowden, Paul, Knight, A. G. and Liovic, M. 2009. A novel mutation (p.Thr198Ser) in the 1A helix of keratin 5 causes the localized variant of Epidermolysis Bullosa Simplex. Experimental Dermatology 18 (7) , pp. 650-652. 10.1111/j.1600-0625.2008.00820.x

Bowden, Paul Edward, Henderson, Hayley and Reilly, John D. 2009. Defining the complex epithelia that comprise the canine claw with molecular markers of differentiation. Veterinary Dermatology 20 (5-6) , pp. 347-359. 10.1111/j.1365-3164.2009.00851.x

Han, Song, Cooper, David Neil

and Bowden, Paul Edward 2006. Utilization of a cryptic noncanonical donor splice site in the KRT14 gene causes a mild form of epidermolysis bullosa simplex. British Journal of Dermatology 155 (1) , pp. 201-3. 10.1111/j.1365-2133.2006.07269.x

Schweizer, Jürgen, Bowden, Paul Edward, Coulombe, Pierre, Langbein, Lutz, Lane, E. Birgitte, Magin, Thomas M., Maltais, Lois, Omary, M. Bishr, Parry, David A. D., Rogers, Michael A. and Wright, Mathew W. 2006. New consensus nomenclature for mammalian keratins. Journal of Cell Biology 174 (2) , pp. 169-174. 10.1083/jcb.200603161

Patel, Girish Khandubhai, Wilson, Catherine Helen, Harding, Keith Gordon, Finlay, Andrew Yule

and Bowden, Paul Edward 2006. Numerous keratinocyte subtypes involved in wound re-epithelialization. Journal of Investigative Dermatology 126 (2) , pp. 497-502. 10.1038/sj.jid.5700101

Anstey, Alexander Vincent

, Azurdia, R.M., Rhodes, L.E., Pearse, Anthony David and Bowden, Paul Edward 2005. Photosensitive Smith-Lemli-Opitz syndrome is not caused by a single gene mutation: analysis of the gene encoding 7-dehydrocholesterol reductase in five U.K. families. British Journal of Dermatology 153 (4) , pp. 774-9. 10.1111/j.1365-2133.2005.06761.x

Bowden, Paul Edward 2005. The human type II keratin gene cluster on chromosome 12q13.13: final count or hidden secrets? Journal of Investigative Dermatology 124 (3) , xv-xvii. 10.1111/j.0022-202X.2005.23647.x

Liovic, M., Bowden, Paul Edward, Marks, R. and Komel, R. 2004. A mutation (N177S) in the structurally conserved helix initiation peptide motif of keratin 5 causes a mild EBS phenotype. Experimental Dermatology 13 (5) , pp. 332-334. 10.1111/j.0906-6705.2004.00171.x

Virtanen, Marie, Smith, Susan Kaye, Gedde-Dahl Jr, Tobias, Vahlquist, Anders and Bowden, Paul Edward 2003. Splice site and deletion mutations in keratin (KRT1 and KRT10) genes: unusual phenotypic alterations in Scandinavian patients with epidermolytic hyperkeratosis. Journal of investigative dermatology 121 (5) , pp. 1013-20. 10.1046/j.1523-1747.2003.12534.x

Virtanen, M., Gedde-Dahl, T. Jr., Bowden, Paul Edward, Mork, N. J., Vahlquist, A. and Leigh, I. 2001. Phenotypic/genotypic correlations in patients with epidermolytic hyperkeratosis and the effects of retinoid therapy on keratin expression. Acta Dermato-Venereologica 81 (3) , pp. 163-170. 10.1080/000155501750376221

Liovic, Mirjana, Stojan, Jure, Bowden, Paul Edward, Gibbs, Daniel, Vahlquist, Anders, Lane, E. Birgitte and Komel, Radovan 2001. A novel keratin 5 mutation (K5V186L) in a family with EBS-K: a conservative substitution can lead to development of different disease phenotypes. Journal of Investigative Dermatology 116 (6) , pp. 964-969. 10.1046/j.1523-1747.2001.01334.x

Pearce, Eve G, Smith, S Kaye, Lanigan, Sean W and Bowden, Paul Edward 1999. Two different mutations in the same codon of a Type II hair keratin (hHb6) in patients with monilethrix. Journal of Investigative Dermatology 113 (6) , pp. 1123-1127. 10.1046/j.1523-1747.1999.00777.x

Bowden, Paul Edward, Hainey, Sandra D., Parker, Gillian, Jones, David O., Zimonjic, Drazen, Popescu, Nicholas and Hodgins, Malcolm B. 1998. Characterization and chromosomal localization of human hair-specific keratin genes and comparative expression during the hair growth cycle. Journal of Investigative Dermatology 110 (2) , pp. 158-164. 10.1046/j.1523-1747.1998.00097.x

Bickenbach, Jackie R., Longley, Mary Ann, Bundman, Donnie S., Dominey, Andrea M., Bowden, Paul Edward, Rothnagel, Joseph A. and Roop, D. R. 1996. A transgenic mouse model that recapitulates the clinical features of both neonatal and adult forms of the skin disease epidermolytic hyperkeratosis. Differentiation 61 (2) , pp. 129-139. 10.1046/j.1432-0436.1996.6120129.x

Bowden, Paul Edward, Haley, Joanne L., Kansky, Aleksej, Rothnagel, Joseph A., Jones, David O. and Turner, Richard J. 1995. Mutation of a type II keratin gene (K6a) in pachyonychia congenita. Nature Genetics 10 (3) , pp. 363-365. 10.1038/ng0795-363

Bowden, Paul Edward, Hainey, Sandra, Parker, Gillian and Hodgins, Malcolm B. 1994. Sequence and expression of human hair keratin genes. Journal of Dermatological Science 7 , S152-S163. 10.1016/0923-1811(94)90046-9

Bowden, Paul Edward, Woodworth, C. D., Doniger, J. and DiPaolo, J. A. 1992. Down-regulation of keratin 14 gene expression after v-Ha-ras transfection of human papillomavirus-immortalized human cervical epithelial cells. Cancer Research 52 (21) , pp. 5865-5871.

Bowden, Paul Edward, Hainey, Sandra, Withers, Anne P., Parker, Gillian and Hodgins, Malcolm B. 1992. Cloning and expression of human hair keratin genes [Abstract]. Journal of Investigative Dermatology 98 (4) , p. 515. 10.1111/1523-1747.ep12499878

Bowden, Paul Edward, Rothnagel, Joseph A. and Roop, Dennis R. 1991. Regulatory elements of HK1, a human epidermal keratin gene [Abstract]. Journal of Investigative Dermatology 96 (6) , p. 1030. 10.1111/1523-1747.ep12476622

Rothnagel, J. A., Greenhalgh, D. A., Bowden, Paul Edward, Longley, M. A., Bundman, D. S. and Roop, D. R. 1991. Use of transgenic mice to identify regulatory sequences 5' to the human K1 keratin gene [Abstract]. Journal of Investigative Dermatology 96 (4) , p. 541. 10.1111/1523-1747.ep12470305

Pfeifer, A. M. A., Jones, R. T., Bowden, Paul Edward, Mann, D., Spillare, E., Klein-Szanto, A. J. P., Trump, B. F. and Harris, C. C. 1991. Human bronchial epithelial cells transformed by the c-raf-1 and c-myc protooncogenes induce multidifferentiated carcinomas in nude mice: a model for lung carcinogenesis. Cancer Research 51 (14) , pp. 3793-3801.

Bowden, Paul Edward, Woodworth, Craig D., Doniger, Jay and DiPaolo, Joseph A. 1990. Down-regulation of K14 gene-expression in cervical cell-carcinoma [Abstract]. Journal of Investigative Dermatology 95 (4) , p. 463. 10.1111/1523-1747.ep12555802

Withers, Anne P. and Bowden, Paul Edward 1990. Keratin expression in mammalian skin, hair and nail [Abstract]. Journal of Investigative Dermatology 95 (4) , p. 496. 10.1111/1523-1747.ep12555802

Bowden, Paul Edward 1990. Gene expression and hair-loss. Nature 346 (6282) , p. 315. 10.1038/346315a0

Popescu, N. C., Bowden, Paul Edward and DiPaolo, J. A. 1989. Two type II keratin genes are localized on human chromosome 12. Human Genetics 82 (2) , pp. 109-112.

Woodworth, C. D., Bowden, Paul Edward, Doniger, J., Pirisi, L., Barnes, W., Lancaster, W. D. and DiPaolo, J. A. 1988. Characterization of normal human exocervical epithelial cells immortalized in vitro by papillomavirus types 16 and 18 DNA. Cancer Research 48 (16) , pp. 4620-4628.

Bowden, Paul Edward, Blanchard, Alain and Steinert, Peter M. 1988. Human epidermal keratin genes isolated from different genomic libraries exhibit restriction length polymorphism [Abstract]. Journal of Investigative Dermatology 90 (4) , p. 548. 10.1111/1523-1747.ep12461142

Bowden, Paul Edward, Blanchard, Alain and Steinert, Peter M. 1987. Linkage of epidermal keratin genes isolated on large human cosmid clones [Abstract]. Journal of Investigative Dermatology 88 (4) , p. 478. 10.1111/1523-1747.ep12469921

Bowden, Paul Edward, Stark, H.-J., Breitkreutz, D. and Fusenig, N. E. 1987. Expression and modification of keratins during terminal differentiation of mammalian epidermis. Current Topics in Developmental Biology 22 , pp. 35-68. 10.1016/S0070-2153(08)60098-8

Breitkreutz, D., Hornung, J., Pohlmann, J., Brown-Bierman, L., Bohnert, A., Bowden, Paul Edward and Fusenig, N. E. 1986. Environmental induction of differentiation-specific keratins in malignant mouse keratinocyte lines. European Journal of Cell Biology 42 (2) , pp. 255-267.

Bowden, Paul Edward, Stark, H. J., Breitkreutz, D. and Hornung, J. 1986. Alterations in keratin expression as primary epidermal cultures are established [Abstract]. Journal of Investigative Dermatology 86 (4) , p. 465. 10.1111/1523-1747.ep12285810

Bowden, Paul Edward, Quinlan, Roy A., Breitkreutz, Dirk and Fusenig, Norbert E. 1984. Proteolytic modification of acidic and basic keratins during terminal differentiation of mouse and human epidermis. European Journal of Biochemistry 142 (1) , pp. 29-36. 10.1111/j.1432-1033.1984.tb08246.x

Beitkreutz, Dirk, Bohnert, Axel, Herzmann, Erika, Bowden, Paul Edward, Boukamp, Petra and Fusenig, Norbert E. 1984. Differentiation specific functions in cultured and transplanted mouse keratinocytes: environmental influences on ultrastructure and keratin expression. Differentiation 26 (1-3) , pp. 154-169. 10.1111/j.1432-0436.1984.tb01389.x

Bowden, Paul Edward, Herzmann, E., Breitkreutz, D. and Fusenig, N. E. 1983. Modulation of keratin expression in basal, spinous and granular epidermal cells [Abstract]. British Journal of Dermatology 109 (6) , p. 698. 10.1111/j.1365-2133.1983.tb00552.x

Bowden, Paul Edward and Quinlan, R. 1983. Glycine- and serine-rich regions of epidermal prekeratin chains are major phosphorylation sites [Abstract]. Journal of Investigative Dermatology 80 (4) , pp. 334-335. 10.1111/1523-1747.ep12534716

Breitkreutz, D., Bowden, Paul Edward, Quinlan, R., Franke, W. W. and Fusenig, N. E. 1983. Precursor-product relationship between prekeratin and keratin in mouse and human-epidermis [Abstract]. Journal of Investigative Dermatology 80 (4) , p. 334. 10.1111/1523-1747.ep12534716

Bowden, Paul Edward, Wood, Edward J. and Cunliffe, William J. 1983. Comparison of prekeratin and keratin polypeptides in normal and psoriatic human epidermis. Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology 743 (1) , pp. 172-179. 10.1016/0167-4838(83)90431-4

Bladon, P. T., Bowden, Paul Edward, Cunliffe, W. J. and Wood, E. J. 1982. Prekeratin biosynthesis in human scalp epidermis. Biochemical Journal 208 (1) , pp. 179-187.

Bowden, Paul Edward, Bladon, P. T., Wood, E. J. and Cunliffe, W. J. 1982. Biosynthesis and characterization of the isoelectric variants of prekeratin polypeptides from human epidermis [Abstract]. British Journal of Dermatology 106 (6) , p. 726. 10.1111/j.1365-2133.1982.tb14713.x

Bowden, Paul Edward, Bladon, P. T., Wood, E. J. and Cunliffe, W. J. 1982. Post-translational phosphorylation of keratin gene-products in human-epidermis [Abstract]. Journal of Investigative Dermatology 78 (4) , p. 330. 10.1111/1523-1747.ep12507412

Bowden, Paul Edward and Cunliffe, W. J. 1981. Modification of human prekeratin during epidermal differentiation. Biochemical Journal 199 (1) , pp. 145-154.

Bowden, Paul Edward and Cunliffe, W. J. 1981. The composition of prekeratin and keratin from psoriatic epidermis [Abstract]. British Journal of Dermatology 105 (3) , p. 346. 10.1111/j.1365-2133.1981.tb01295.x

Bladon, P. T., Bowden, Paul Edward, Wood, E. J. and Cunliffe, W. J. 1981. The biosynthesis of human epidermal prekeratin [Abstract]. British Journal of Dermatology 105 (3) , pp. 345-346. 10.1111/j.1365-2133.1981.tb01295.x

Bladon, P. T., Bowden, Paul Edward, Wood, E. J. and Cunliffe, W. J. 1981. The biosynthesis and phosphorylation of human epidermal prekeratin [Abstract]. Journal of Investigative Dermatology 76 (5) , pp. 417-418. 10.1111/1523-1747.ep12520969

Bowden, Paul Edward and Cunliffe, W. J. 1980. Preliminary-analysis of keratinocyte proteins extracted from isolated pilosebaceous ducts [Abstract]. Journal of Investigative Dermatology 74 (6) , p. 457. 10.1111/1523-1747.ep12545390

Bowden, Paul Edward, Bladon, P. T., Wood, E. J. and Cunliffe, W. J. 1980. Biosynthesis of human scale skin proteins by in-vitro translation of isolated messenger-RNA [Abstract]. Journal of Investigative Dermatology 74 (6) , p. 456. 10.1111/1523-1747.ep12545390

Simpson, N. B., Bowden, Paul Edward, Forster, R. A. and Cunliffe, W. J. 1979. The effect of topically applied progesterone on sebum excretion rate. British Journal of Dermatology 100 (6) , pp. 687-692. 10.1111/j.1365-2133.1979.tb08073.x

Simpson, N. B., Bowden, Paul Edward, Cunliffe, W. J. and Forster, R. A. 1978. Tolerance to the anti-seborrhoeic effect of topically applied progesterone [Abstract]. British Journal of Dermatology 99 (s16) , p. 9. 10.1111/j.1365-2133.1978.tb15200.x

Meddis, D., Thody, A. J., Bowden, Paul Edward and Shuster, S. 1977. Alpha-melanocyte - stimulating hormone and territorial marking in mongolian gerbil [Abstract]. Journal of Investigative Dermatology 68 (4) , pp. 252-253. 10.1111/1523-1747.ep12493643

Thody, A. J., Cooper, Mary F., Bowden, Paul Edward, Meddis, D. and Shuster, S. 1976. Effect of alpha-melanocyte-stimulating hormone and testosterone on cutaneous and modified sebaceous glands in the rat. Journal of Endocrinology 71 (3) , pp. 279-288. 10.1677/joe.0.0710279

Bowden, Paul Edward, Meddis, David, Cooper, Mary F., Thody, Anthony J. and Shuster, Sam 1976. Effects of 5alpha-reduced androgens on preputial-gland size and lipogenic activity. Biochemical Society Transactions 4 (4) , pp. 795-797. 10.1042/bst0040795

Cooper, Mary F., Bowden, Paul Edward, Meddis, David, Thody, Anthony J. and Shuster, Sam 1976. Effects of testosterone and alpha-melanocyte-stimulating hormone on preputial-gland (sebaceous) activity. Biochemical Society Transactions 4 (4) , pp. 798-800. 10.1042/bst0040798

Bowden, Paul Edward, Meddis, D., Cooper, M. F., Thody, A. J. and Shuster, Sam 1975. Synergistic effect of alpha-MSH and testosterone on sebaceous gland activity [Abstract]. Journal of Investigative Dermatology 64 (4) , p. 288. 10.1111/1523-1747.ep12512079

This list was generated on Wed Apr 23 08:28:10 2025 BST.