ORCA
Online Research @ CardiffÂ
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McGuigan, Christopher  ORCID: https://orcid.org/0000-0001-8409-710X, Madela, Karolina, Aljarah, Mohamed, Bourdin, Claire, Arrica, Maria, Barrett, Emma, Jones, Sarah Louise, Kolykhalov, Alexander, Bleiman, Blair, Bryant, K. Dawn, Ganguly, Babita, Gorovits, Elena, Henson, Geoffrey, Hunley, Damound, Hutchins, Jeff, Muhammad, Jerry, Obikhod, Aleksandr, Patti, Joseph, Walters, C. Robin, Wang, Jin, Vernachio, John, Ramamurty, Changalvala V. S., Battina, Srinivas K. and Chamberlain, Stanley
2011.
Phosphorodiamidates as a promising new phosphate prodrug motif for antiviral drug discovery: application to anti-HCV agents.
Journal of Medicinal Chemistry
54
(24)
, pp. 8632-8645.
10.1021/jm2011673
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Vernachio, J., Bryant, D., Chamberlain, S. D., Gorovits, E., Ganguly, B. S., Hall, A., Henson, G. W., Hunley, D. S., Hutchins, J. T., Muhammad, J., Patti, J., Walters, C. R., Wang, J., Madela, Karolina, Aljarah, Mohamed, Jones, Sarah Louise and McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X
2010.
In vitro and in vivo metabolism of INX-189, a potent HCV inhibitor, in rat and cynomolgus monkey hepatocytes [Abstract].
Hepatology
52
(S1)
, 1218A-1219A.
10.1002/hep.23997
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Hall, A., Raja, N., Chamberlain, S. D., Gorovits, E., Henson, G. W., Hutchins, J. T., Muhammad, J., Patti, J., Vernachio, J., Wang, J., Madela, Karolina, Aljarah, Mohamed, Jones, Sarah Louise and McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X
2010.
Metabolite characterization of INX-189, a potent HCV inhibitor, in fresh human primary hepatocytes and human liver and kidney cell lines [abstract 1874].
Hepatology
52
(S1)
, 1211A-1211A.
10.1002/hep.23996
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McGuigan, Christopher ORCID: https://orcid.org/0000-0001-8409-710X, Gilles, Arnaud, Madela, Karolina, Aljarah, Mohamed, Holl, Sabrina, Jones, Sarah Louise, Vernachio, John, Hutchins, Jeff, Ames, Brenda, Bryant, K. Dawn, Gorovits, Elena, Ganguly, Babita, Hunley, Damound, Hall, Andrea, Kolykhalov, Alexander, Liu, Yule, Muhammad, Jerry, Raja, Nicholas, Walters, Robin, Wang, Jin, Chamberlain, Stanley and Henson, Geoffrey
2010.
Phosphoramidate ProTides of 2'-C-Methylguanosine as highly potent inhibitors of hepatitis C virus. Study of their in vitro and in vivo properties.
Journal of Medicinal Chemistry
53
(13)
, pp. 4949-4957.
10.1021/jm1003792
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