Bayliss, Rebecca J.  ORCID: https://orcid.org/0000-0002-3324-957X and Piguet, Vincent
2018.
The ticking CLOCK of HSV-2 pathology.
Journal of Investigative Dermatology
138
(1)
, pp. 17-19.
10.1016/j.jid.2017.08.028
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Official URL: http://dx.doi.org/10.1016/j.jid.2017.08.028
Abstract
Herpes simplex virus type 2 (HSV-2) is the causative agent of genital herpes. Matsuzawa et al have demonstrated that, in a mouse model, HSV-2 pathology is influenced by the time infection occurs. Increased expression of the HSV-2 receptor Nectin-1 under the control of CLOCK coincided with an increase in viral titer suggesting that HSV-2 infection is regulated by the host circadian clock.
| Item Type: | Article |
|---|---|
| Date Type: | Publication |
| Status: | Published |
| Schools: | Schools > Medicine |
| Publisher: | Nature Publishing Group |
| ISSN: | 0022-202X |
| Date of First Compliant Deposit: | 16 July 2018 |
| Date of Acceptance: | 20 November 2017 |
| Last Modified: | 05 Dec 2024 23:45 |
| URI: | https://orca.cardiff.ac.uk/id/eprint/113193 |
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