Smith, Keith  ORCID: https://orcid.org/0000-0003-4838-5651, El-Hiti, Gamal A., Hegazy, Amany Saber and Shalabi, Ahmed Fekri
2010.
A simple and convenient high yielding synthesis of substituted isoindolines.
Heterocycles
80
(2)
, pp. 941-956.
10.3987/COM-09-S(S)61
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Official URL: http://www.heterocycles.jp/library/abstract.php?do...
Abstract
Trifluoroacetic anhydride-induced dehydration of substituted 2-(pivaloylaminomethyl)phenyl- and 2-(dimethylaminocarbonylmethyl)phenylmethanols gives the corresponding isoindolines in excellent yields when there are aryl substituents at the methanol carbon atom.
| Item Type: | Article |
|---|---|
| Status: | Published |
| Schools: | Schools > Chemistry |
| Subjects: | Q Science > QD Chemistry |
| Uncontrolled Keywords: | Cyclization ; Dehydration ; Heterocycle ; Substituted Benzyl-N,N-dimethylurea ; Synthesis |
| Publisher: | Sendai Institute of Heterocyclic Chemistry |
| ISSN: | 0385-5414 |
| Date of First Compliant Deposit: | 30 March 2016 |
| Last Modified: | 05 Aug 2026 04:40 |
| URI: | https://orca.cardiff.ac.uk/id/eprint/12724 |
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