Synthesis of homogenous site-selectively glycosylated proteins

Swanwick, Richard S., Daines, Alison M., Flitsch, Sabine L. and Allemann, Rudolf Konrad ORCID: https://orcid.org/0000-0002-1323-8830 2005. Synthesis of homogenous site-selectively glycosylated proteins. Organic & Biomolecular Chemistry 3 (4) , pp. 572-574. 10.1039/b417133k

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Abstract

Apparently homogenous glycoproteins can be synthesised in good yield by a combination of site directed mutagenesis, a highly flexible but selective chemical derivatisation and efficient purification through the use of glycosyl thiosulfonates such as 2-((biotinoyl)-amino)-ethyl methanethiosulfonate.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Chemistry Cardiff Catalysis Institute (CCI)
Subjects:	Q Science > QD Chemistry
Publisher:	RSC Publications
ISSN:	1477-0520
Last Modified:	18 Oct 2022 13:19
URI:	https://orca.cardiff.ac.uk/id/eprint/13488

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