Grange, Jacques ![]() ![]() Item availability restricted. |
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Abstract
Pathologies underlying sensorineural hearing loss (SNHL) cannot yet be differentially diagnosed. An advanced SNHL simulator takes the stimulus encoding by Meddis and colleagues’ Model of the Auditory Periphery [1] at the auditory nerve (AN) level and decodes it into a signal used in psychophysical tasks to determine the signatures of specific pathologies. Speech reception thresholds (SRTs) for stimuli processed through the normal-hearing (NH) simulator, were just 1 dB higher than those obtained for unprocessed stimuli. With both efferent reflexes disabled, SRTs grew by ~4 dB. Simulated rate-level functions illustrate how efferent reflexes enable the AN dynamic-range adaptation to context level that prevents information loss. While deactivating 70% of ANs or halving the endo-cochlear potential led to little SRT inflation, SRTs significantly rose as a result of total outer haircells knockout. 90% deafferentation was required to reflect performance found in hearing impaired listeners, a finding consistent with the expected effect of stochastic under-sampling [2]. ITD discrimination thresholds were found to be more sensitive to deafferentation than SRTs.
Item Type: | Conference or Workshop Item (Paper) |
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Status: | In Press |
Schools: | Psychology |
Subjects: | B Philosophy. Psychology. Religion > BF Psychology Q Science > QP Physiology R Medicine > RB Pathology R Medicine > RF Otorhinolaryngology |
Publisher: | e-Forum Acusticum 2020 |
Funders: | EPSRC |
Date of First Compliant Deposit: | 29 January 2021 |
Date of Acceptance: | 10 December 2020 |
Last Modified: | 27 Nov 2022 13:16 |
URI: | https://orca.cardiff.ac.uk/id/eprint/138058 |
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